Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Multiple Sclerosis l: Introduction

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...

Negative and Cognitive Symptoms of Schizophrenia

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Prevalence and Incidence

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...

Factors Affecting Illness

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness, disability,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Primary cutaneous nodular amyloidosis associated with the injection of autologous fat.

Clinical and experimental dermatology·2020

Same author

Management of Euxesta spp. in Sweet Corn with McPhail Traps.

Neotropical entomology·2019

Same author

Rectal tuberculosis: An uncommon clinical presentation and differential diagnosis with Crohn's disease.

Revista de gastroenterologia de Mexico (English)·2019

Same author

Hypervascular Pseudonodular Plaque-Like Ultrasound Morphology in Angiolymphoid Hyperplasia.

Actas dermo-sifiliograficas·2018

Same author

Implications of zoonotic and vector-borne parasites to free-roaming cats in central Spain.

Veterinary parasitology·2018

Same author

Brain Donation by Proxy: Are There Predictors in Neurodegenerative Dementia?

The journal of prevention of Alzheimer's disease·2017

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Cognitive dysfunction in systemic lupus erythematosus: prevalence and correlates.

J Olazarán¹, J López-Longo, I Cruz

¹Neurology, Services, Gregorio Marañón General University Teaching Hospital, Madrid, Spain. javier@mariawolff.es

European Neurology

|May 2, 2009

Summary

Cognitive dysfunction is common in women with non-neuropsychiatric systemic lupus erythematosus (nSLE), impacting social functioning. This study highlights the need to assess cognitive health in nSLE patients.

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Related Experiment Videos

Last Updated: Jun 23, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

Neuroscience
Rheumatology
Psychology

Background:

Systemic lupus erythematosus (SLE) can affect the brain, but cognitive dysfunction in patients without major neuropsychiatric symptoms (nSLE) is poorly understood.
Understanding cognitive impairment in nSLE is crucial for comprehensive patient care.

Purpose of the Study:

To investigate the prevalence and characteristics of cognitive dysfunction in female patients with nSLE compared to healthy controls.
To explore potential correlations between cognitive dysfunction, clinical markers, and sociodemographic factors in nSLE.

Main Methods:

Recruited 31 female nSLE patients and 31 healthy female controls.
Collected sociodemographic, clinical, neuropsychological data, and SLE-related markers.
Utilized single-photon emission computed tomography (SPECT) to assess cerebral perfusion.

Main Results:

Cognitive dysfunction was significantly more prevalent in nSLE patients (32.3%) than in controls (6.5%, p=0.01).
Cognitive complaints correlated with depressive symptoms (r=0.35, p=0.05) and dysfunction with less skilled occupation (r=-0.41, p=0.02) in nSLE.
All cognitive domains were similarly affected in the nSLE group.

Conclusions:

Cognitive dysfunction is frequent in nSLE patients and can negatively impact social functioning.
Further research into the mechanisms and management of cognitive impairment in nSLE is warranted.