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Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
Published on: July 21, 2016
The obstetric face and challenge of HIV/AIDS
Franco Guidozzi1, Vivian Black
1Department of Obstetrics and Gynaecology daggerReproductive Health and HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa. Franco.Guidozzi@wits.ac.za
Abstract:
The human immunodeficiency virus (HIV) pandemic is one of the most serious health crises facing the world. Of the estimated 33.2 million people living with HIV worldwide, 22.5 million (68%) live in Sub-Saharan Africa, where women of childbearing age are most severely affected. Children primarily acquire HIV infection through mother-to-child transmission. Despite recent encouraging success, low-income countries have not been able to effectively curtail transmission of HIV to the infant during or after pregnancy, resulting in about 90% of the estimated 420,000 newly infected children per annum occurring in Sub-Saharan Africa.
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