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Related Experiment Videos

Misoprostol-induced urinary incontinence.

V Fossaluzza1, P Di Benedetto, A Zampa

  • 1Rheumatic Disease Unit, Ospedale Civile S. Maria della Misericordia, Udine, Italy.

Journal of Internal Medicine
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

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Misoprostol can cause urinary incontinence in women with rheumatoid arthritis. Urodynamic studies showed reduced urethral resistance, suggesting caution is needed for patients with stress incontinence.

Area of Science:

  • Rheumatology
  • Urology
  • Pharmacology

Background:

  • Rheumatoid arthritis is a chronic autoimmune disease.
  • Misoprostol is a medication with various therapeutic uses.
  • Urinary incontinence is a common condition affecting women.

Observation:

  • A young woman with rheumatoid arthritis developed urinary incontinence.
  • The patient was administered misoprostol.
  • Urodynamic studies were conducted to investigate the cause.

Findings:

  • The urodynamic study revealed a deficiency in urethral resistance.
  • This deficiency may be the cause of the induced urinary incontinence.
  • The side-effect might be more prevalent than currently recognized.

Related Experiment Videos

Implications:

  • Misoprostol should be used cautiously in patients with rheumatoid arthritis.
  • Healthcare providers should be aware of this potential side-effect.
  • Further research may be warranted to determine the incidence of misoprostol-induced incontinence.