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Updated: Jun 23, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Comparison of short-time Fourier transform and Eigenvector MUSIC methods using discrete wavelet transform for
Fatma Latifoğlu1, Sadik Kara, Erkan Imal
1Department of Biomedical Engineering, Erciyes University, 38039 Kayseri, Turkey. flatifoglu@erciyes.edu.tr
Abstract:
In this paper, a more effective use of Doppler techniques is presented for the purpose of diagnosing atherosclerosis in its early stages using the carotid artery Doppler signals. The power spectral density (PSD) graphics are obtained by applying the short-time Fourier transform (STFT)-Welch and the Eigenvector MUSIC methods to the discrete wavelet transform (DWT) of Doppler signals. The PSDs for the fourth approximation component (A4) of both methods estimated that the patients with atherosclerosis in its early phase had lower maximum frequency components. On the other hand, the healthy subjects had higher maximum frequency components. The area under the curve (AUC), which belongs to the receiver operating characteristic (ROC) curve for the frequency level of the maximum PSDs of the A4 approximation obtained from the STFT modeling, is computed as 0.97. The AUC for the MUSIC modeling is computed as 0.996. The AUC belonging to the ROC curve for the higher maximum frequency component is computed as 0.87. The AUC belonging to the ROC curve for the test parameter of the frequency level of the maximum PSDs derived from the MUSIC modeling is determined to be 0.882. The results of this study clearly demonstrate that it is possible to distinguish between the healthy people and the patients with atherosclerosis by using the frequency level of the maximum PSDs for the A4 approximation. Furthermore, it is concluded that the power of Eigenvector-MUSIC method in terms of the resolution of the high frequencies is better than that of the STFT methods.
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