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Updated: Jun 23, 2026

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
Published on: October 26, 2016
[Results of alginate and hypertonic solution in wound healing of head and neck cancers]
B K Diallo1, S Lacher-Fougere, B Baltazart
1CHU Pellegrin, Pôle F.-X. Michelet, Service ORL et Chirurgie Cervico-Faciale, 33076 Bordeaux cedex, France. baydiallo@yahoo.fr
Introduction:
In head and neck cancers, complications such as pharyngostoma, orostoma, or fistula can present following surgery or surgery after irradiation.
Objective:
To report the results of the association of two sea-derived products (Sinomarin and Algosteril) compared to normal saline for the management of healing.
Material And Methods:
This is retrospective study (1998-2000). Thirty patients were included in group 1 (Sinomarin-Algosteril) and 17 patients in group 2 (normal saline). The average age was respectively 60 and 56.2. Patients in both groups presented with advanced head and neck carcinoma (T3-T4) and healing complications.
Results:
The delay of healing was respectively of 33.53 and 72.94 days. Results were statistically significant (Student T-test P < 0.05).
Conclusion:
Our results show the efficiency (p < 0.05) of the Sinomarin Algosteril association in head and neck cancer healing complications.
