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[Effects of calcium and vitamin D supplementation on bone specific alkaline during pregnancy lactation and infant]

Jinping Wang1, Haihong Li, Qing He

  • 1Beijing Obstetrics and Gynecology Hospital of Capital Medical University, Beijing 100026, China. happy360360@126.com

Wei Sheng Yan Jiu = Journal of Hygiene Research
|May 5, 2009
PubMed

Insights

Maternal calcium and vitamin D supplementation during lactation, and infant supplementation, significantly decrease infant bone-specific alkaline phosphatase (BAP). Fontanel size did not indicate infant calcium status.

Area of Science:

  • Nutritional science
  • Pediatric bone health
  • Maternal-infant health

Context:

  • Bone development is crucial in early life.
  • Calcium and vitamin D are essential nutrients for skeletal health.
  • Supplementation strategies during pregnancy, lactation, and infancy are explored.

Purpose:

  • To evaluate the impact of calcium and vitamin D supplementation on infant bone development.
  • To assess the effects of supplementation during different maternal and infant stages.
  • To determine the relationship between supplementation and infant bone markers.

Summary:

  • Maternal calcium and vitamin D intake during lactation and infant supplementation significantly reduced infant bone-specific alkaline phosphatase (BAP).
  • Supplementation during pregnancy did not show a significant effect on infant BAP.
  • Infant feeding methods did not significantly influence BAP levels.
  • Fontanel anterior (FA) size in infants under 42 days showed a negative correlation with BAP, but FA size did not reliably indicate infant calcium status.

Impact:

  • Provides evidence for optimal timing of calcium and vitamin D supplementation for infant bone health.
  • Highlights the importance of maternal supplementation during lactation and direct infant supplementation.
  • Suggests that fontanel size may not be a reliable indicator of calcium status in infants.
Abstract

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