Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photothermally Antibacterial Piezoelectric Composite Dressing Synergized with Endogenous Electrical Stimulation for Wound Healing.

Pharmaceutics·2026
Same author

Enhanced nodal staging by molecular detection of KLK3, FOLH1, and PCA3 in prostate cancer.

Discover oncology·2026
Same author

Prognostic value and predictive model construction for patients undergoing laparoscopic radical prostatectomy based on the preoperative NPL-IRS score and prognostic nutritional index.

Frontiers in oncology·2025
Same author

Longitudinal and Nonlinear Coupling for High-Fidelity Readout of a Superconducting Qubit.

Physical review letters·2025
Same author

Indocyanine green fluorescence in pelvic lymph node dissection during laparoscopic radical prostatectomy: a randomized controlled trial.

Updates in surgery·2025
Same author

Realization of fractional quantum Hall state with interacting photons.

Science (New York, N.Y.)·2024

Related Experiment Video

Updated: Jun 23, 2026

Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits
06:03

Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits

Published on: July 21, 2023

[Progressing study in treating discogenic low back pain].

Zhi-qiang Xin1, Liang Zhao, Jian-wen Wang

  • 1Department of Spinal Surgery, the Orthopaedics Hospital of Yuexiu District of Guoangzhou, Guangzhou 510045, Guangdong, China.

Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology
|May 5, 2009
PubMed
Summary
This summary is machine-generated.

Discogenic low back pain, caused by intervertebral disc issues, affects many adults. This summary reviews current treatment methods for this common back pain condition.

Related Experiment Videos

Last Updated: Jun 23, 2026

Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits
06:03

Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits

Published on: July 21, 2023

Area of Science:

  • Orthopedics
  • Pain Management
  • Rehabilitation Medicine

Context:

  • Lumbago, or low back pain, is a prevalent clinical symptom affecting 60-80% of adults.
  • Discogenic low back pain originates from pathological changes stimulating pain receptors in the intervertebral discs.
  • Diverse treatment modalities exist, but their indications and efficacy vary significantly.

Purpose:

  • To summarize current therapeutic approaches for discogenic low back pain.
  • To provide an overview based on recent international and domestic research.
  • To incorporate clinical expertise for a comprehensive review.

Summary:

  • This review synthesizes data on various treatments for discogenic low back pain.
  • It analyzes the indications and therapeutic effects of different interventions.
  • The summary draws from recent literature and author's clinical experience.

Impact:

  • Aims to guide clinicians in selecting appropriate treatments for discogenic low back pain.
  • Contributes to a better understanding of treatment efficacy and patient selection.
  • Facilitates evidence-based decision-making in managing this common condition.