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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

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Published on: October 20, 2017

Posterior fossa arteriovenous malformations.

Omar M Arnaout1, Bradley A Gross, Christopher S Eddleman

  • 1Department of Neurological Surgery, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Neurosurgical Focus
|May 5, 2009
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Summary

Posterior fossa arteriovenous malformations (AVMs) are rare but dangerous. These brain AVMs have a high risk of bleeding, emphasizing the need for prompt and aggressive treatment.

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Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Neurology

Background:

  • Posterior fossa arteriovenous malformations (AVMs) are uncommon, representing less than 15% of all AVMs.
  • These lesions are often associated with intracranial hemorrhage, increasing the risk of re-bleeding.
  • A posterior fossa or deep location indicates a more aggressive disease course.

Purpose of the Study:

  • To review the literature on posterior fossa AVMs.
  • To highlight the natural history and rupture rates of these lesions.
  • To emphasize the importance of aggressive treatment strategies.

Main Methods:

  • Literature review of studies on posterior fossa AVMs.
  • Analysis of reported annual rupture rates.
  • Evaluation of treatment implications based on lesion characteristics.

Main Results:

  • Posterior fossa AVMs are associated with a significant risk of hemorrhage.
  • Annual rupture rates for these AVMs can be as high as 11.6%.
  • Aggressive treatment is crucial given the potential for severe outcomes.

Conclusions:

  • Posterior fossa AVMs represent a high-risk neurovascular condition.
  • The high annual rupture rate necessitates consideration of aggressive management.
  • Improving therapeutic options support proactive intervention for suitable lesions.