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Related Experiment Video

Updated: Jun 23, 2026

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

Published on: September 8, 2023

Giant serpentine aneurysms.

Lana D Christiano¹, Gaurav Gupta, Charles J Prestigiacomo

¹Department of Neurological Surgery New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07101, USA. docmitchel@yahoo.com

Neurosurgical Focus

|May 5, 2009

Summary

Giant serpentine aneurysms are large, complex vascular lesions. This review summarizes literature and institutional strategies for managing these challenging brain aneurysms.

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Area of Science:

Vascular Neurology
Interventional Neuroradiology
Neurosurgery

Background:

Giant serpentine aneurysms (GSAs) were first described in 1977.
These rare lesions are characterized by large size (>or= 25 mm), partial thrombosis, and a patent, serpiginous channel.
GSAs present unique anatomical challenges including large size, complex neck, and dependent distal vessels.

Purpose of the Study:

To review the existing literature on giant serpentine aneurysms.
To describe institutional management strategies for these rare cerebrovascular lesions.
To highlight the evolution of treatment options from surgical obliteration to endovascular techniques.

Main Methods:

Comprehensive literature review of giant serpentine aneurysms.
Analysis of institutional case series and management approaches.
Discussion of diagnostic and therapeutic modalities.

Main Results:

Giant serpentine aneurysms are rare and pose significant treatment challenges.
Both surgical and endovascular techniques have been employed for management.
Evolving endovascular techniques offer expanded treatment options.

Conclusions:

Giant serpentine aneurysms require specialized management strategies.
A multidisciplinary approach integrating surgical and endovascular expertise is often necessary.
Continued research and case reporting are vital for optimizing treatment outcomes.