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Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

Published on: February 1, 2019

Synthesis of novel cholesterol-based cationic lipids for gene delivery

Bieong-Kil Kim1, Kyung-Oh Doh, Joo Hyeung Nam

  • 1School of Life Sciences and Biotechnology, Kyungpook National University, Sankyukdong, Bookgu, Daegu, Republic of Korea.

Bioorganic & Medicinal Chemistry Letters
|May 5, 2009
PubMed

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Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...