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Epithelioma cuniculatum: A case report.

J Halpern1, S Harris, V Suarez

  • 1Department of Dermatology, COPD, University Hospital of North Staffordshire, Hartshill Road, Stoke-on-Trent, England ST4 7PA, United Kingdom. James_Halpern@hotmail.com

Foot and Ankle Surgery : Official Journal of the European Society of Foot and Ankle Surgeons
|May 5, 2009
PubMed
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Epithelioma cuniculatum, a rare foot cancer, can be misdiagnosed. This case highlights the need for repeat biopsies and aggressive treatment, including amputation, for this verrucous carcinoma.

Area of Science:

  • Dermatology
  • Oncology
  • Podiatry

Background:

  • Epithelioma cuniculatum, a rare verrucous carcinoma, primarily affects the foot.
  • First described in 1954, it is characterized by slow growth and a warty appearance.

Observation:

  • A 55-year-old man presented with a progressively enlarging lesion on his right foot sole.
  • The lesion evolved, becoming softer and developing a foul odor, despite initial benign biopsy results.

Findings:

  • Repeat biopsy confirmed a well-differentiated squamous cell carcinoma.
  • The patient ultimately required a below-the-knee amputation due to local invasion.

Implications:

  • Diagnosis of epithelioma cuniculatum can be delayed, often necessitating multiple biopsies.

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  • While metastasis is rare, aggressive local invasion requires wide surgical excision, potentially including amputation.