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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Dimeric 1,4-benzoquinone derivatives and a resorcinol derivative from Ardisia gigantifolia
Hongwei Liu1, Feng Zhao, Ruiyun Yang
1Key Lab of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, PR China. liuhongwei60@yahoo.com.cn
Abstract:
Naturally occurring dimeric 1,4-benzoquinone derivatives, belamcandaquinones F, G, H, and I, as well as one resorcinol derivative and four known compounds, were isolated from rhizomes of Ardisia gigantifolia. Their structures were established by means of spectroscopic analyses. All compounds were tested against cell lines PC-3, EMT6, A549, Hela, RM-1, and SGC7901 for cytotoxicity in vitro. In comparison with cisplatin, compounds 5 and 6 showed a strong cytotoxicity with IC(50) values less than 30 microM for most cell lines tested.
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