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Tricuspid valve disease: pathophysiology and optimal management
K M John Chan1, Mustafa Zakkar, Emre Amirak
1Department of Cardiothoracic Surgery, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College London, United Kingdom.
Progress in Cardiovascular Diseases
|May 5, 2009
Summary
Tricuspid regurgitation (TR) often results from left-sided heart issues and indicates a poor prognosis. Management involves surgery for severe primary TR or secondary TR during left-sided valve repair.
Area of Science:
- Cardiology
- Cardiac Surgery
- Valvular Heart Disease
Background:
- Tricuspid valve disease frequently develops secondary to left-sided heart valve conditions, especially mitral valve disease.
- Moderate to severe tricuspid regurgitation (TR) is associated with adverse outcomes and decreased survival rates.
- Primary TR requires surgical intervention when severe and symptomatic.
Purpose of the Study:
- To review the pathophysiology of tricuspid valve disease.
- To outline current management strategies for tricuspid valve disease.
Main Methods:
- Literature review of tricuspid valve disease pathophysiology.
- Analysis of current clinical guidelines and surgical indications for TR management.
Main Results:
- Secondary TR, particularly with elevated pulmonary artery pressures or annular dilatation, warrants treatment during concomitant left-sided valve surgery.
- Surgical treatment is indicated for severe, symptomatic primary TR.
Conclusions:
- Tricuspid valve disease is a significant predictor of outcomes in patients with left-sided heart disease.
- Timely intervention for both primary and secondary TR is crucial for improving patient survival and quality of life.
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