Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Regulation of Hematopoietic Stem Cells

Regulation of Hematopoietic Stem Cells

All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Multipotency of Hematopoietic Stem Cells

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...

Hematopoiesis

Hematopoiesis

The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chemotherapy Extravasation: Establishing a National Benchmark for Incidence Among Cancer Centers.

Clinical journal of oncology nursing·2017

Same author

On the Scene: Developing a Nurse Care Coordinator Role at City of Hope.

Nursing administration quarterly·2015

Same author

High-dose chemo-radiotherapy for relapsed or refractory Hodgkin lymphoma and the significance of pre-transplant functional imaging.

British journal of haematology·2010

Same author

Neutropenia: state of the knowledge part I.

Oncology nursing forum·2006

Same author

Neutropenia: state of the knowledge part II.

Oncology nursing forum·2006

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Published on: May 19, 2023

Management issues in hematopoietic stem cell transplantation.

Robert David Rice¹, Gay Bailey

¹Quality Management and Magnet Program, Department of Nursing, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. ricer@mskcc.org

Seminars in Oncology Nursing

|May 5, 2009

Summary

Creating and maintaining a hematopoietic stem cell transplant (HSCT) program requires expert nursing leadership. Nurses must manage specialized care, coordination, and quality improvement throughout the patient continuum.

More Related Videos

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Published on: December 8, 2023

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Published on: August 31, 2016

Related Experiment Videos

Last Updated: Jun 23, 2026

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Published on: May 19, 2023

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Published on: December 8, 2023

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness

Published on: August 31, 2016

Area of Science:

Hematopoietic Stem Cell Transplantation
Nursing Leadership
Healthcare Management

Background:

Establishing and sustaining a comprehensive hematopoietic stem cell transplant (HSCT) program presents unique leadership and management obstacles.
The evolving landscape of HSCT necessitates adaptive strategies for program development and maintenance.

Purpose of the Study:

To delineate the leadership and management challenges inherent in developing and sustaining a robust HSCT program.
To identify key areas requiring attention for successful HSCT program operation.

Main Methods:

A comprehensive review of existing research studies, relevant review articles, and accessible databases and web sites was conducted.
Information was synthesized to identify recurring themes and critical factors in HSCT program management.

Main Results:

Nursing leadership is crucial across all practice levels for expert care delivery in all phases of HSCT.
Specialized functions like care coordination, case management, and adherence to scope of practice are vital.
Continuous quality assessment and improvement initiatives are essential for program success.

Conclusions:

Expert nursing leadership is indispensable for managing the continuum of care in HSCT, especially with patient transitions between healthcare settings.
Increasing demands for outpatient care, cost containment, and quality from consumers and regulators challenge nurse leaders.
Nurse leaders must embrace innovative approaches to manage complex HSCT enterprises effectively.