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Updated: Jun 23, 2026

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
Published on: November 22, 2024
Cognitive dysfunction after cardiovascular surgery
K S Funder1, J Steinmetz, L S Rasmussen
1Department of Anesthesia, Center of Head and Orthopedics, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Unlabelled:
This review describes the incidence, risk factors, and long-term consequences of cognitive dysfunction after cardiovascular surgery. Postoperative cognitive dysfunction (POCD) is increasingly being recognized as an important complication, especially in the elderly. A highly sensitive neuropsychological test battery must be used to detect POCD and a well-matched control group is very useful for the analysis and interpretation of the test
Results:
Cardiovascular surgery is associated with a high incidence of POCD. Cardiopulmonary bypass was thought to explain this difference, but randomized studies comparing with off-pump coronary artery bypass surgery show contradictory
Results:
POCD seems to have important long-term consequences regarding self-assessed quality of life, survival, and labor market attachment.
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