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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Pathological sub-types, risk factors and outcome of stroke at the Nairobi Hospital, Kenya

J O Jowi1, P M Mativo

  • 1Department of Medicine, Aga Khan University Hospital, Nairobi, P.O. Box 30270-00100, Nairobi, Kenya.

East African Medical Journal
|May 6, 2009
PubMed

Insights

This study found ischemic stroke to be the most common type, with hypertension as the leading risk factor in Nairobi. The in-hospital stroke prevalence was 3042/100,000, with most patients discharged.

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Stroke is a leading cause of death and disability globally.
  • Risk factors like hypertension, diabetes, and smoking are prevalent, especially in tropical regions.
  • Co-morbidities such as HIV/AIDS and sickle cell disease are increasingly observed.

Purpose of the Study:

  • To determine the pathological subtypes of stroke.
  • To identify prevalent risk factors and co-morbidities associated with stroke.
  • To ascertain the in-hospital period prevalence and outcomes of stroke patients.

Main Methods:

  • A hospital-based retrospective study was conducted at The Nairobi Hospital.
  • Data from 80 patients diagnosed with stroke (cerebral vascular accident) between 18 and 95 years old were analyzed.
  • WHO diagnostic criteria were used for stroke diagnosis.

Main Results:

  • Ischemic stroke accounted for 85% of cases, with hypertension (80%) and diabetes mellitus (33.7%) as primary risk factors.
  • The in-hospital period prevalence of stroke was 3042/100,000.
  • The mean hospital stay was 12.5 days, with a 93.8% discharge rate and a 5% in-hospital mortality rate.

Conclusions:

  • Ischemic stroke is the most common subtype in this study population.
  • Hypertension is the predominant risk factor for stroke.
  • The study highlights a significant in-hospital stroke prevalence and generally favorable outcomes with timely management.
Abstract

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