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Published on: July 19, 2018
[Acute hyperphosphatemia in a dialysis patient after administration of sodium phosphate]
Brian Behfar Sohrabi Azad1, Joakim Cordtz
1Glostrup Hospital, Ortopaedkirurgisk Afdeling A og Anaestesiologisk Afdeling Y. brianazad@gmail.com
Abstract:
We describe a case of severe hyperphosphatemia due to phosphate-based enema for the preparation of coloscopy. A 39-year-old man with end-stage renal failure was admitted with bloody diarrhoea. After administration of a phosphate-based enema, he was seized with general convulsions due to severe hyperphosphatemia and subsequent hypocalcaemia. The patient recovered after daily dialysis and administration of intravenous calcium. The case demonstrates the need to avoid using phosphate-based laxatives in patients with impaired renal function.
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Phosphate Buffer
Sodium dihydrogen phosphate does not fully dissociate in neutral or acidic solutions. When a strong base, such as sodium hydroxide (NaOH), is introduced into the solution, sodium dihydrogen phosphate...