Related Experiment Video
Updated: Jan 28, 2026
A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
Published on: February 2, 2022
Renal carcinoma: minimally invasive surgery of the small renal mass
1Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. pintop@mail.nih.gov
Abstract:
Open partial nephrectomy has become the gold standard surgical management for small renal masses less than 4 cm. With the surgical advances in the field of laparoscopy and robotic surgery, minimally invasive partial nephrectomy is now feasible. Long-term 5 year cancer-specific survival rates have recently been reported for laparoscopic partial nephrectomy. These results are comparable to open partial nephrectomy series. As the field of robotic assisted surgery continues to expand beyond the treatment of prostate cancer, these techniques are being investigated in the treatment of small renal masses. Currently, minimally invasive partial nephrectomy has become an option in the treatment of small renal masses.
Insights
Minimally invasive partial nephrectomy, using laparoscopy or robotic surgery, is now a viable option for small renal masses. Long-term survival rates for laparoscopic partial nephrectomy are comparable to open surgery.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Open partial nephrectomy is the standard for small renal masses (<4 cm).
- Surgical technology advancements enable minimally invasive approaches.
Purpose of the Study:
- To evaluate the feasibility and outcomes of minimally invasive partial nephrectomy for small renal masses.
- To compare minimally invasive techniques with the established open partial nephrectomy.
Main Methods:
- Review of recent studies reporting on laparoscopic and robotic partial nephrectomy outcomes.
- Comparison of 5-year cancer-specific survival rates between open and minimally invasive partial nephrectomy.
Main Results:
- Laparoscopic partial nephrectomy demonstrates long-term cancer-specific survival rates comparable to open partial nephrectomy.
- Minimally invasive partial nephrectomy is increasingly feasible and effective for small renal masses.
Conclusions:
- Minimally invasive partial nephrectomy, including laparoscopic and robotic approaches, is a safe and effective option for managing small renal masses.
- These techniques offer comparable oncological outcomes to traditional open surgery.
Related Concept Videos
01:17Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
01:20Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
01:23Renal Clearance
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
01:08Renal Drug Clearance: Comparison Between Renal Excretion Methods
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
01:23Drug Elimination: Non-Renal Routes
01:24Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...