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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

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Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
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Related Experiment Video

Updated: Jun 23, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

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Published on: April 23, 2014

Improving quality and diffusing best practices: the case of schizophrenia.

Marcela Horvitz-Lennon1, Julie M Donohue, Marisa E Domino

  • 1Western Psychiatric Institute and Clinic, University of Pittsburgh (Pennsylvania) Medical School, USA. horvitzlennonmv@upmc.edu

Health Affairs (Project Hope)
|May 6, 2009
PubMed
Summary

Evidence-based mental health treatments spread slowly, while unproven ones spread quickly, leading to lower quality care for severe mental illness. This impacts cost-effectiveness and treatment availability, particularly for schizophrenia.

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Published on: May 15, 2020

Area of Science:

  • Mental Health Services Research
  • Health Policy
  • Psychiatry

Background:

  • Care quality for severe mental illness (SMI) lags behind less severe conditions.
  • Empirical evidence-based treatments disseminate slowly.
  • Ineffective or low cost-effectiveness treatments spread rapidly.

Purpose of the Study:

  • To analyze paradoxical diffusion patterns of mental health treatments.
  • To identify factors contributing to lower quality SMI care.
  • To propose policy solutions for improving mental health treatment dissemination.

Main Methods:

  • Review of diffusion patterns in mental health care.
  • Case study focusing on schizophrenia treatment.
  • Analysis of cost-effectiveness in treatment adoption.

Main Results:

  • Slow adoption of evidence-based practices in SMI care.
  • Rapid uptake of treatments lacking empirical support.
  • Low cost-effectiveness treatments limit resources for high-value care.

Conclusions:

  • Paradoxical treatment diffusion negatively impacts SMI care quality.
  • Policy interventions are needed to promote evidence-based practices.
  • Addressing cost-effectiveness is crucial for optimizing mental health resource allocation.