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Published on: July 19, 2018

Causes of chronic renal failure among Iranian hemodialysis patients

Leila Malekmakan1, Sezaneh Haghpanah, Maryam Pakfetrat

  • 1Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Iran. malekl@sums.ac.ir

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|May 6, 2009
PubMed

Insights

Chronic renal failure (CRF) in hemodialysis patients is primarily caused by hypertension and diabetes mellitus. Effective management of these conditions is crucial for preventing end-stage renal disease and improving patient outcomes.

Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Background:

  • Chronic renal failure (CRF) signifies progressive, irreversible kidney function decline.
  • Hemodialysis (HD) is a critical treatment for end-stage renal disease.
  • Understanding CRF causes in HD patients is vital for preventative strategies.

Purpose of the Study:

  • To investigate the prevalence and etiological factors of CRF among hemodialysis patients in Fars Province, Iran.
  • To assess the current status of CRF management in the studied population.

Main Methods:

  • A cross-sectional study design was employed.
  • Data collected via questionnaires from 633 hemodialysis patients (371 males, 262 females).
  • Demographic data, medical history, and key clinical indicators like KT/V and BMI were recorded.

Main Results:

  • The mean KT/V was 1.04, with only 32.1% achieving the target KT/V > 1.2.
  • Mean Body Mass Index (BMI) was 24 ± 4.5.
  • Hypertension (30.5%) and diabetes mellitus (30.1%) were identified as the leading causes of CRF.

Conclusions:

  • Hypertension and diabetes mellitus are the predominant causes of CRF in Fars Province.
  • Improved management of hypertension and diabetes can potentially avert the progression to end-stage renal disease.
  • Targeted interventions focusing on these primary causes are recommended for CRF prevention.

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