Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Complement System

Complement System

The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a membrane...

EDTA: Auxiliary Complexing Reagents

EDTA: Auxiliary Complexing Reagents

EDTA titrations are usually carried out in highly basic conditions, where the fully deprotonated form of EDTA, Y4−, actively complexes with the free metal ions in the solution. Several metal ions precipitate as hydrous oxide (hydroxides, oxides, or oxyhydroxides) under these conditions, lowering the concentration of free metal ions in the solution. For this reason, auxiliary complexing agents or ligands such as ammonia, tartrate, citrate, or triethanolamine are used in EDTA titrations to...

Lattice Centering and Coordination Number

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...

Additional Subnuclear Structures

Additional Subnuclear Structures

The eukaryotic nucleus is a double membrane-bound organelle that contains nearly all of the cell’s genetic material in the form of chromosomes. It is rightly called the “brain” of the cell as it shoulders the responsibility of responding to various physiological processes, stress, altered metabolic conditions, and other cellular signals.
The nucleus contains many membrane-less subnuclear organelles or nuclear bodies, such as nucleoli, Cajal bodies, speckles, paraspeckles, etc. These nuclear...

Additional Subnuclear Structures

Additional Subnuclear Structures

The eukaryotic nucleus is a double membrane-bound organelle that contains nearly all of the cell’s genetic material in the form of chromosomes. It is rightly called the “brain” of the cell as it shoulders the responsibility of responding to various physiological processes, stress, altered metabolic conditions, and other cellular signals.
The nucleus contains many membrane-less subnuclear organelles or nuclear bodies, such as nucleoli, Cajal bodies, speckles, paraspeckles, etc. These nuclear...

Eccentric Loading

Eccentric Loading

Eccentric loading is a crucial concept in the study of structural engineering and mechanics, particularly when analyzing the stability and stress distribution in columns. Unlike centric loading, where the force is applied along the centroidal axis, causing uniform compression, eccentric loading occurs when a force is applied off-center. This off-center application introduces not only direct compressive stress but also bending stress, significantly influencing the column's behavior under load.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

DEG 15, an update of the Database of Essential Genes that includes built-in analysis tools.

Nucleic acids research·2020

Same author

Wild-type p53-induced phosphatase 1 down-regulation promotes apoptosis by activating the DNA damage-response pathway in amyotrophic lateral sclerosis.

Neurobiology of disease·2019

Same author

Spy1, a unique cell cycle regulator, alters viability in ALS motor neurons and cell lines in response to mutant SOD1-induced DNA damage.

DNA repair·2019

Same author

"Perfect" designer chromosome V and behavior of a ring derivative.

Science (New York, N.Y.)·2017

Same author

Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.

International journal of molecular sciences·2016

Same author

Differential response in levels of high-density lipoprotein cholesterol to one-year metformin treatment in prediabetic patients by race/ethnicity.

Cardiovascular diabetology·2015

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

The e-index, complementing the h-index for excess citations.

Chun-Ting Zhang¹

¹Department of Physics, Tianjin University, Tianjin, China. ctzhang@tju.edu.cn

|May 6, 2009

Summary

This summary is machine-generated.

The new e-index complements the widely used h-index by accounting for all citations, offering a more accurate measure of scientific performance. This enhanced metric is crucial for evaluating highly cited researchers and comparing scientists with similar h-indices.

More Related Videos

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Related Experiment Videos

Last Updated: Jun 23, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Area of Science:

Bibliometrics
Scientometrics
Research Evaluation

Background:

The h-index is a standard metric for evaluating individual scientific performance, used by major citation databases.
However, the h-index has limitations, including information loss and low resolution, hindering fair comparisons of research output.
Excess citations beyond the h-core are ignored, and many researchers can share the same h-index.

Purpose of the Study:

To address the limitations of the h-index in accurately assessing scientific productivity.
To introduce a new metric that captures all citation information, providing a more comprehensive evaluation.
To offer a tool for precise comparison of researchers, especially those with high citation counts or identical h-indices.

Main Methods:

Introduction of the e-index, which accounts for excess citations ignored by the h-index.
The e-index is designed to work independently of the h-index, ensuring complete citation depiction.
Comparison with other h-type indices (e.g., a, R) to highlight their h-dependency and information redundancy.

Main Results:

The combination of the h-index and e-index provides a complete picture of citation impact.
The e-index captures information on excess citations, which are disregarded by the h-index.
Unlike other h-type indices, the e-index and h-index are independent, avoiding masked differences in researcher output.

Conclusions:

The e-index serves as a necessary complement to the h-index.
It is particularly valuable for evaluating highly cited scientists.
The e-index enables more precise comparisons among researchers with identical h-indices.