Jove
Visualize
Contact Us

Related Concept Videos

Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also regularly...
Muscles of the Pelvic Floor and Perineum01:26

Muscles of the Pelvic Floor and Perineum

The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...
Binary Fission01:20

Binary Fission

Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical.
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A few hours from disaster.

BMJ (Clinical research ed.)·2012
Same author

Mature and immature extracranial teratomas in children: the UK Children's Cancer Study Group Experience.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2008
Same journal

Should pull through be offered to patients with cloacal exstrophy?

Pediatric surgery international·2026
Same journal

Potential benefits of simultaneous anorecto-vaginoplasty for patients with persistent cloaca: insights from a nationwide survey in Japan.

Pediatric surgery international·2026
Same journal

Elective interval appendectomy following non-operative management for uncomplicated acute appendicitis: a feasible same-day discharge strategy in children.

Pediatric surgery international·2026
Same journal

Predictors of organ injury in pediatric bicycle handlebar trauma: a single-center retrospective study.

Pediatric surgery international·2026
Same journal

Can urinary exosomal lncRNAs HOTAIR and MALAT1 predict surgical need and outcomes in unilateral antenatal hydronephrosis?

Pediatric surgery international·2026
Same journal

An interim analysis of the standard care (stoma bags) and double-diapers in pediatric patients with stomas at a tertiary hospital in South Africa.

Pediatric surgery international·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 23, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

Duplicated proctodeum.

Danielle Vietan1, Ramnik Vallabh Patel, Simon N Huddart

  • 1Department of Paediatric Surgery, University Hospital of Wales, Heath Park, Cardiff, CF 14 4XW, Wales, UK.

Pediatric Surgery International
|May 6, 2009
PubMed
Summary
This summary is machine-generated.

A rare case of anal duplication in an infant was successfully treated. Surgical excision of the duplicated proctodeum resulted in excellent functional and cosmetic outcomes for the patient.

More Related Videos

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium
07:20

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

Published on: April 9, 2019

Two-dimensional Porcine Intestinal Organoids Reflecting the Physiological Properties of Native Gut
09:13

Two-dimensional Porcine Intestinal Organoids Reflecting the Physiological Properties of Native Gut

Published on: January 31, 2025

Related Experiment Videos

Last Updated: Jun 23, 2026

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis
08:17

Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis

Published on: January 14, 2017

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium
07:20

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

Published on: April 9, 2019

Two-dimensional Porcine Intestinal Organoids Reflecting the Physiological Properties of Native Gut
09:13

Two-dimensional Porcine Intestinal Organoids Reflecting the Physiological Properties of Native Gut

Published on: January 31, 2025

Area of Science:

  • Pediatric Surgery
  • Congenital Anomalies
  • Gastrointestinal Malformations

Background:

  • Anal duplication is a rare congenital anomaly.
  • It can present with varied clinical features.
  • Early diagnosis and management are crucial for optimal outcomes.

Observation:

  • A 3-month-old female infant presented with two near mirror-image anal openings.
  • Imaging studies including ultrasound, X-rays, and contrast X-ray revealed a 2-cm long non-communicating proctodeal duplication.
  • The anterior anus was normally sited, while a posterior duplicated proctodeum was identified.

Findings:

  • The infant underwent examination under anesthesia (EUA), proctoscopy, and sphincter stimulation.
  • Transproctodeal excision of the duplication was performed.
  • External sphincter reconstruction was achieved with excellent cosmetic and functional results.

Implications:

  • This case highlights the successful surgical management of anal duplication in an infant.
  • The described technique offers a viable approach for correcting this rare malformation.
  • Achieving excellent functional and cosmetic results is paramount in pediatric anorectal surgery.