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Injectable calcium hydroxylapatite microspheres (Radiesse).

Brock Ridenour1, Theda C Kontis

  • 1Ridenour Plastic Surgery, St. Louis, Missouri 63141, USA. Brock.ridenour@ridenourplasticsurgery.com

Facial Plastic Surgery : FPS
|May 6, 2009
PubMed
Summary
This summary is machine-generated.

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Injectable calcium hydroxylapatite (Radiesse) is FDA-approved for correcting facial wrinkles and lipoatrophy. This synthetic bone filler offers a durable solution for moderate to severe facial lines and other cosmetic applications.

Area of Science:

  • Dermatology
  • Cosmetic Surgery
  • Biomaterials Science

Background:

  • Injectable calcium hydroxylapatite (Radiesse) gained FDA approval in 2006.
  • It is indicated for facial lipoatrophy and moderate to severe facial wrinkles.

Purpose of the Study:

  • To summarize the properties and applications of injectable calcium hydroxylapatite (Radiesse).

Main Methods:

  • Product composition: synthetic bone microspheres in a methylcellulose gel matrix.
  • Injection technique: subdermal plane.
  • Clinical application: correction of moderate to severe wrinkles (e.g., nasolabial folds), facial lipoatrophy, and off-label uses on the face, nose, and hands.

Main Results:

  • Radiesse's thicker consistency compared to hyaluronic acids makes it suitable for deeper wrinkles.

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  • Correction duration is approximately 1 year post-injection.

    • Conclusions:

    • Calcium hydroxylapatite (Radiesse) is a versatile injectable filler for various cosmetic facial concerns.
    • Its efficacy in correcting wrinkles and lipoatrophy is supported by its unique composition and subdermal placement.