Organic tissue glue in the closure of cataract incisions in rabbit eyes

We performed 7 mm scleral pocket cataract incisions in both eyes of ten rabbits. One eye of each rabbit was closed with one interrupted 10-0 nylon suture and organic tissue glue (Tisseel) and the other was closed with a conventional shoelace running 10-0 nylon suture. The eyes were examined clinically and histopathologically at various postoperative intervals. No difference in wound integrity was found between the two closures, but slightly more inflammation occurred in the eyes closed with glue than in those closed with sutures alone. Organic tissue glue may become an alternative method to suture closure of scleral pocket cataract incisions.