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Related Concept Videos

Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
Horizontal Gene Transfer01:27

Horizontal Gene Transfer

Horizontal gene transfer (HGT) is a process where genetic material moves between organisms within the same generation, unlike vertical gene transfer, which occurs from parent to offspring. HGT plays a crucial role in microbial evolution, adaptation, and survival, particularly in shared environments like the human gut.Mobile genetic elements such as plasmids, prophages, integrons, insertion sequences, and transposons facilitate this process. HGT occurs through three primary mechanisms:...
Eukaryotic Evolution01:24

Eukaryotic Evolution

The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...

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Related Experiment Video

Updated: Jun 23, 2026

Detection of Horizontal Gene Transfer Mediated by Natural Conjugative Plasmids in E. coli
06:56

Detection of Horizontal Gene Transfer Mediated by Natural Conjugative Plasmids in E. coli

Published on: March 24, 2023

Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant?

Vera I D Ros1, Gregory D D Hurst

  • 1Department of Biology, Leidy Laboratories 326, University of Pennsylvania, 433 South University Avenue, Philadelphia, PA 19104-6018, USA. veraros@sas.upenn.edu

BMC Biology
|May 7, 2009
PubMed
Summary

Genes transferred from bacteria to the pea aphid are actively expressed, suggesting potential functional roles. This finding supports the evolutionary importance of gene transfer in symbiotic relationships.

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Methodology for the Study of Horizontal Gene Transfer in Staphylococcus aureus
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Last Updated: Jun 23, 2026

Detection of Horizontal Gene Transfer Mediated by Natural Conjugative Plasmids in E. coli
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High-Resolution Comparison of Bacterial Conjugation Frequencies
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Methodology for the Study of Horizontal Gene Transfer in Staphylococcus aureus
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Methodology for the Study of Horizontal Gene Transfer in Staphylococcus aureus

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Area of Science:

  • Genomics
  • Evolutionary Biology
  • Molecular Biology

Background:

  • Genome sequencing reveals extensive lateral gene transfer between prokaryotic and eukaryotic organisms.
  • The functional significance of these transferred genes in recipient hosts remains largely unconfirmed.

Discussion:

  • Nikoh and Nakabachi demonstrate high expression of two bacterial genes in the pea aphid (Acyrthosiphon pisum).
  • This finding is corroborated by three independent studies indicating active gene expression of horizontally transferred genes.
  • The study represents a crucial initial step in verifying the functional impact of gene transfer.

Key Insights:

  • Two bacterial genes show significant expression in the pea aphid, indicating they are not silenced post-transfer.
  • Active gene expression suggests these genes may be acquiring novel functions in the eukaryotic host.
  • This research provides empirical evidence for the functional potential of transferred genes.

Outlook:

  • Future research should investigate protein production and subcellular localization of these expressed genes.
  • Understanding the functional roles of transferred genes is key to deciphering their evolutionary impact.
  • Gene transfer between hosts and symbionts may play a critical role in the evolution of symbiotic interactions.