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Application of biomedical informatics to chronic pediatric diseases: a systematic review
Fatemeh Moeinedin1, Rahim Moineddin, Alejandro R Jadad
1Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada. moeinedin@gmail.com
Insights
Biomedical informatics applications show positive clinical and patient outcomes for children with chronic diseases, particularly in asthma management. These tools improve care and patient satisfaction, highlighting their potential for broader chronic illness management.
Area of Science:
- Pediatric Health Informatics
- Chronic Disease Management
- Health Outcomes Research
Background:
- Millions of children globally suffer from chronic diseases, increasing healthcare burdens.
- Complex pediatric chronic diseases necessitate innovative care delivery models.
- Biomedical informatics offers potential for cost-effective improvements in pediatric chronic disease care.
Purpose of the Study:
- To systematically review the effects of biomedical informatics applications on pediatric chronic diseases.
- To assess the utility and impact of informatics in managing chronic conditions in children and adolescents.
Main Methods:
- Comprehensive literature search of MEDLINE, Cochrane Library, and EMBASE up to September 2008.
- Inclusion of studies of any type and language applying biomedical informatics to chronic conditions in individuals 18 years or younger.
- Independent reviewer selection, data extraction, and quality assessment; meta-analysis not performed due to heterogeneity.
Main Results:
- 27 relevant articles identified from 655 reviewed titles and abstracts.
- Biomedical informatics applications demonstrated favorable clinical and patient outcomes, including reduced ER visits and improved disease knowledge.
- The majority of studies (96%) reported improved outcomes, with 89% of users being patients.
Conclusions:
- Published evidence indicates positive impacts of informatics, especially in pediatric asthma management.
- Increasing adoption of electronic tools presents opportunities to enhance patient care across various chronic illnesses.
- Informatics solutions hold significant promise for improving outcomes in pediatric chronic disease management.
Background:
Chronic diseases affect millions of children worldwide leading to substantial disease burden to the children and their families as well as escalating health care costs. The increasing trend in the prevalence of complex pediatric chronic diseases requires innovative and optimal delivery of care. Biomedical informatics applications play an important role in improving health outcomes while being cost-effective. However, their utility in pediatric chronic diseases has not been studied in a comprehensive and systematic way. The objective of this study was to conduct a systematic review of the effects of biomedical informatics applications in pediatric chronic diseases.
Methods:
A comprehensive literature search was conducted using MEDLINE, the Cochrane Library and EMBASE databases from inception of each database to September 2008. We included studies of any methodological type and any language that applied biomedical informatics to chronic conditions in children and adolescents 18 years of age or younger. Two independent reviewers carried out study selection and data extraction. Quality assessment was performed using a study design evaluation instrument to appraise the strength of the studies and their methodological adequacy. Because of heterogeneity in the conditions and outcomes we studied, a formal meta-analysis was not performed.
Results:
Based on our search strategy, 655 titles and abstracts were reviewed. From this set we identified 27 relevant articles that met our inclusion criteria. The results from these studies indicated that biomedical informatics applications have favourable clinical and patient outcomes including, but not limited to, reduced number of emergency room visits, improved knowledge on disease management, and enhanced satisfaction. Seventy percent of reviewed papers were published after year 2000, 89% of users were patients and 11% were either providers or caregivers. The majority (96%) of the selected studies reported improved outcomes.
Conclusion:
Published studies suggested positive impacts of informatics predominantly in pediatric asthma. As electronic tools become more widely adopted, there will be opportunities to improve patient care in a wide range of chronic illnesses through informatics solutions.
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