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A Conditioned Place Preference Protocol for Measuring Incubation of Craving in Rats
Published on: November 6, 2018
Conditioned place preference induced by morphine in non-copulating male rats
Wendy Portillo1, Raúl G Paredes
1Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Qro. 76230, México. portillo654@yahoo.com.mx
Behavioural Brain Research
|May 7, 2009
Abstract:
Non-copulators (NC) are normal males that fail to display sexual behavior, we evaluate if NC male rats have a functional general reward system. NC male rats were injected with morphine to determine if a reward state, as evaluated by the conditioned place preference (CPP) paradigm, could be induced. Our results demonstrate that NC males develop CPP to a morphine injection, indicating that their general reward system is functional.

