Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Nanoparticle agglomerates in magnetoliposomes.

E R Cintra¹, F S Ferreira, J L Santos Junior

¹Instituto de Física, Universidade Federal de Goiás, 74001-970 Goiânia-GO, Brazil.

|May 7, 2009

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stereotactic radiotherapy for liver oligometastases: a pooled analysis following the estro/eortc consensus recommendations.

Clinical & experimental metastasis·2024

Same author

Influence of urbanization on stream fish assemblages in three microbasins in the Upper Paraná River Basin.

Brazilian journal of biology = Revista brasleira de biologia·2021

Same author

Behavioral disorders and impairment of quality of life in children and adolescents with lower urinary tract dysfunction.

Journal of pediatric urology·2018

Same author

Vertebrates as a Bactericidal Agent.

EcoHealth·2018

Same author

Aquatic life protection index of an urban river Bacanga basin in northern Brazil, São Luís - MA.

Brazilian journal of biology = Revista brasleira de biologia·2016

Same author

Recurrent amplification of RTEL1 and ABCA13 and its synergistic effect associated with clinicopathological data of gastric adenocarcinoma.

Molecular cytogenetics·2016

Researchers developed a magneto-optical technique to precisely control and quantify magnetic nanoparticles encapsulated within liposomes. This method helps optimize magnetic nanocarrier systems for various biomedical applications.

Area of Science:

Biomaterials Science
Nanotechnology
Biophysics

Background:

Magnetoliposomes, vesicles with magnetic nanoparticles, are vital for MRI contrast agents, drug delivery, and cancer therapy.
Controlling the quantity and arrangement of encapsulated magnetic nanoparticles is crucial for optimizing magnetoliposome performance.
Existing methods for characterizing nanoparticle encapsulation in liposomes have limitations.

Purpose of the Study:

To develop and validate a magneto-optical technique for quantifying encapsulated magnetic nanoparticles in liposomes.
To investigate the influence of sonication duration and cholesterol on nanoparticle encapsulation efficiency and structure.
To assess the long-term stability of magnetic nanoparticle-loaded liposomes.

Main Methods:

More Related Videos

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

Related Experiment Videos

Last Updated: Jun 23, 2026

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

Utilized a magneto-optical technique to analyze liposome-nanoparticle systems.

Systematically varied sonication duration and cholesterol content during liposome preparation.

Monitored nanoparticle encapsulation and structural formation over time.

Main Results:

Quantified between 35 and 300 magnetic nanoparticles encapsulated per liposome, contingent on experimental parameters.
Observed that encapsulated nanoparticles primarily formed small linear chains, mainly trimers and tetramers.
Demonstrated the impact of sonication and cholesterol on encapsulation efficiency and nanoparticle arrangement.

Conclusions:

The developed magneto-optical methodology provides precise insights into magnetic nanoparticle encapsulation within liposomes.
This technique is valuable for optimizing the design and properties of magnetic nanocarrier systems.
Findings contribute to the advancement of magnetoliposome-based technologies for biomedical applications.