Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Building a Synthetic Cell Together.

Nature communications·2025

Same author

Future Directions of the Prokaryotic Chromosome Field.

Molecular microbiology·2025

Same author

Pain-related fear in adolescents with chronic musculoskeletal pain: process evaluation of an interdisciplinary graded exposure program.

BMC health services research·2020

Same author

A microfluidic platform for the characterisation of membrane active antimicrobials.

Lab on a chip·2019

Same author

The supercoiling state of DNA determines the handedness of both H3 and CENP-A nucleosomes.

Nanoscale·2017

Same author

DNA nanopore translocation in glutamate solutions.

Nanoscale·2015

Same journal

Corrigendum: Influence of nanoscale topology on the bactericidal efficiency of black silicon surfaces (2017 Nanotechnology28 245301).

Nanotechnology·2026

Same journal

Corrigendum: Thermal scanning probe lithography for the directed self-assembly of block copolymers (2017<i>Nanotechnology</i>28 175301).

Nanotechnology·2026

Same journal

Gold-nanoparticle-modified ITO electrodes: Effect of preparation methods on the electrochemical performance.

Nanotechnology·2026

Same journal

Nanoparticle manipulation with a carbon fiber tip in an electron microscope for µ-SQUID magnetometry.

Nanotechnology·2026

Same journal

Dual-frequency resonance tracking in switching spectroscopy piezoresponse force microscopy for ferroelectric thin films.

Nanotechnology·2026

Same journal

DFT and machine learning investigation of Au/Pt-decorated SnS₂ monolayers for asthma and COPD diagnosis.

Nanotechnology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

Low-frequency noise in solid-state nanopores.

R M M Smeets¹, N H Dekker, C Dekker

¹Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands.

|May 7, 2009

Summary

This summary is machine-generated.

Low-frequency noise in solid-state nanopores limits translocation experiments. Hooge's relation accurately describes this 1/f noise across various salt concentrations, outperforming surface charge fluctuation models.

More Related Videos

Monitoring Protein Adsorption with Solid-state Nanopores

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

High Resolution Physical Characterization of Single Metallic Nanoparticles

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

Related Experiment Videos

Last Updated: Jun 23, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

Monitoring Protein Adsorption with Solid-state Nanopores

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

High Resolution Physical Characterization of Single Metallic Nanoparticles

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

Area of Science:

Physics
Materials Science
Nanotechnology

Background:

Low-frequency ionic current noise (1/f noise) in solid-state nanopores hinders time resolution in translocation experiments.
Hooge's phenomenological relation has been proposed to explain this noise, relating it to the number of charge carriers.

Purpose of the Study:

To investigate the origin of low-frequency noise in solid-state nanopores.
To compare Hooge's relation with a surface charge fluctuation model for noise in nanopores.
To determine the best model for describing nanopore noise across a wide range of salt concentrations.

Main Methods:

Experimental measurements of ionic current noise in solid-state nanopores.
Analysis of noise characteristics across a salt concentration range from 10(-3) to 1.6 M KCl.
Comparison of experimental data with predictions from Hooge's relation and a surface charge fluctuation model.

Main Results:

Low-frequency noise in solid-state nanopores was observed.
Hooge's relation provided a superior description of the observed noise compared to the surface charge fluctuation model.
The validity of Hooge's relation was confirmed across the entire tested salt concentration range.

Conclusions:

Hooge's relation is the most effective model for describing low-frequency noise in solid-state nanopores.
Surface charge fluctuations are not the primary source of this noise.
The findings advance the understanding of noise mechanisms in nanopore devices, crucial for improving translocation experiment resolution.