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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...

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Related Experiment Video

Updated: Jun 23, 2026

A Method to Quantify Visual Information Processing in Children Using Eye Tracking
09:47

A Method to Quantify Visual Information Processing in Children Using Eye Tracking

Published on: July 9, 2016

Visual fields in young children treated with vigabatrin.

Shivi Agrawal1, D Luisa Mayer, Ronald M Hansen

  • 1Department of Ophthalmology, Children's Hospital, Boston and Harvard Medical School, Boston, Massachusetts 02115, USA.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|May 7, 2009
PubMed
Summary

White sphere kinetic perimetry (WSKP) effectively tested young children treated with Vigabatrin (VGB), an epilepsy drug. WSKP identified peripheral visual field constriction in VGB patients, even those with developmental delays.

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Area of Science:

  • Ophthalmology
  • Neurology
  • Pediatrics

Background:

  • Vigabatrin (VGB) is an antiepileptic drug known to cause visual field constriction.
  • Assessing peripheral visual field function in young children, especially those with epilepsy, presents unique challenges.

Purpose of the Study:

  • To evaluate the feasibility and effectiveness of white sphere kinetic perimetry (WSKP) for assessing peripheral visual field function in children with epilepsy treated with Vigabatrin (VGB).
  • To determine if WSKP can detect visual field constriction associated with VGB treatment in this pediatric population.

Main Methods:

  • A study involving 31 children with a history of epilepsy treated with VGB and 10 age-matched control subjects (median age 6 years).
  • Peripheral visual field extent was measured using WSKP with a 6-degree white sphere on major oblique meridia.
  • Comparison of WSKP results with Goldmann kinetic perimetry (GKP) in a subset of patients and between VGB patients and controls.

Main Results:

  • Binocular WSKP was feasible in 28 of 31 VGB patients, identifying smaller median visual field extents compared to controls.
  • 29% of VGB patients tested with binocular WSKP showed visual field extents below the minimum range of controls.
  • Monocular WSKP results did not significantly differ between VGB patients and controls, highlighting the utility of binocular testing.

Conclusions:

  • White sphere kinetic perimetry (WSKP) is a feasible method for evaluating peripheral visual fields in young children, including those with developmental delays.
  • WSKP demonstrates potential as a valuable tool for detecting and monitoring visual field constriction linked to Vigabatrin (VGB) therapy in children.