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Related Experiment Video

Updated: Jun 23, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Published on: September 12, 2025

Repeat uterine artery embolization following technical failure.

Bruce McLucas¹

¹David Geffen School of Medicine, University of California at Los Angeles, Department of Obstetrics and Gynecology, Los Angeles, CA, 90095, USA. mclucas@ucla.edu

Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy

|May 7, 2009

Summary

This summary is machine-generated.

A two-step approach to uterine artery embolization (UAE) effectively manages symptomatic uterine fibroids after initial technical failure. This method provides significant symptom relief and myoma shrinkage, comparable to standard bilateral UAE.

Related Experiment Videos

Last Updated: Jun 23, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Published on: September 12, 2025

Area of Science:

Interventional Radiology
Gynecology
Vascular Imaging

Background:

Uterine artery embolization (UAE) is a common treatment for symptomatic uterine fibroids.
Initial technical failure during UAE can necessitate alternative treatment strategies.
Evaluating the efficacy of a staged approach to UAE is crucial for patient management.

Purpose of the Study:

To assess the success rate of a two-step bilateral uterine artery embolization (UAE) procedure following initial unilateral technical failure.
To compare the outcomes of repeat embolization after technical failure with outcomes of initial bilateral embolization.

Main Methods:

Retrospective chart review of patients undergoing UAE for symptomatic uterine fibroids between 1997 and 2007.
Comparison between patients who underwent repeat embolization after unilateral technical failure and those who had initial bilateral embolization.
Success defined by symptom relief (questionnaires) and/or >30% shrinkage of the largest myoma (imaging).

Main Results:

Sixteen patients underwent repeat embolization after technical failure; 63.6% showed significant myoma shrinkage, and 93.3% reported symptom relief.
In the initial bilateral embolization group (731 patients reviewed), 64.6% had myoma shrinkage, and 99.6% reported symptom relief.
Outcomes suggest comparable efficacy between the two-step approach and initial bilateral UAE.

Conclusions:

A two-step bilateral uterine artery embolization (UAE) is an effective management option for patients experiencing initial technical failure.
This approach offers comparable success rates in terms of symptom relief and myoma shrinkage.
Repeat embolization after technical failure provides a viable alternative for treating uterine fibroids.