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Electric Dipoles and Dipole Moment01:30

Electric Dipoles and Dipole Moment

Consider two charges of equal magnitude but opposite signs. If they cannot be separated by an external electric field, the system is called a permanent dipole. For example, the water molecule is a dipole, making it a good solvent.
Theoretically, studying electric dipoles leads to understanding why the resultant electric forces around us are weak. Since electric forces are strong, remnant net charges are rare. Hence, the interaction between dipoles helps us understand electrical interactions in...
Electromotive Force01:02

Electromotive Force

Electromotive force (emf) is the force that causes current to flow from a higher to a lower  potential. The term "electromotive force" is used for historical reasons, even though emf is not a force at all.
Any circuit with a constant current must contain an emf-producing source. Examples of emf sources include batteries, electric generators, solar cells, thermocouples, and fuel cells. All these sources transform energy of some kind (mechanical, chemical, thermal, and so on) into electric...
Electromotive Force02:36

Electromotive Force

Electricity is generated by either electrons or ions flowing through a solution or a conducting medium. This flow of electrons or specifically electrical charge is defined as an electric current. When electrons move through a wire, they generate an electric current. It can be recalled that in a redox reaction, electrons are lost and gained. In the spontaneous redox reaction of zinc with copper, when zinc is immersed in a copper ion solution, a transfer of electrons from one substance to...
Induced Electric Dipoles01:28

Induced Electric Dipoles

A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
Motional Emf01:22

Motional Emf

Magnetic flux depends on three factors: the strength of the magnetic field, the area through which the field lines pass, and the field's orientation with respect to the surface area. If any of these quantities vary, a corresponding variation in magnetic flux occurs. If the area through which the magnetic field lines are passing changes, then the magnetic flux also changes. This change in the area can be of two types: the flux through the rectangular loop increases as it moves into the magnetic...

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Related Experiment Video

Updated: Jun 23, 2026

Monitoring Electroporation-Induced Changes in Action Potential Generation in Genetically Engineered Tet-On Spiking HEK cells
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Monitoring Electroporation-Induced Changes in Action Potential Generation in Genetically Engineered Tet-On Spiking HEK cells

Published on: September 6, 2024

PHEMTO: protein pH-dependent electric moment tools.

Alexander A Kantardjiev1, Boris P Atanasov

  • 1Biophysical Chemistry Group, Institute of Organic Chemistry, Bulgarian Academy of Sciences, Sofia-1113, Bulgaria.

Nucleic Acids Research
|May 8, 2009
PubMed
Summary

PHEMTO provides advanced tools for analyzing protein electrostatics and molecular interactions. This protein pH-dependent electric moment tool offers new features for evaluating electric dipole moments and their pH dependence.

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Area of Science:

  • Biophysics
  • Computational Biology
  • Protein Science

Background:

  • Accurate evaluation of electrostatic characteristics is crucial for understanding protein molecular recognition.
  • Existing tools may lack advanced features for analyzing pH-dependent electrostatic properties and their impact on interactions.

Purpose of the Study:

  • Introduce PHEMTO, a novel server for detailed analysis of protein electrostatics.
  • Provide advanced features for evaluating electric/dipole moments, pH-dependence, and in silico charge mutagenesis effects.
  • Offer alternative algorithms for electric/dipole moment computation, including singular value decomposition of electrostatic potential.

Main Methods:

  • Utilizes long-term experience from PHEI mean field electrostatics and the PHEPS server.
  • Implements advanced algorithms for calculating electrostatic properties, including reaction field effects.
  • Features an intuitive, user-friendly interface accepting Protein Data Bank files and allowing addition of non-polypeptide charges.

Main Results:

  • PHEMTO offers comprehensive electrostatic characteristics analysis with a focus on electric/dipole moments.
  • Provides interactive visualization of electric/dipole moments and their pH-dependent behavior.
  • Includes novel features beyond standard electrostatics analysis for protein interactions.

Conclusions:

  • PHEMTO serves as a valuable resource for protein scientists needing to evaluate electrostatic properties.
  • The server's advanced features and fast algorithms facilitate deeper insights into protein molecular recognition.
  • PHEMTO enhances the analysis of protein interactions through detailed electrostatic and dipole moment evaluation.