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Updated: Jun 23, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
Identifying the functional role of Martinotti cells in cortical sensory processing
1Wolfson Institute for Biomedical Research, The Cruciform Building, Gower Street, University College London, London, WC1E 6BT, UK. j.cottam@ucl.ac.uk
Abstract:
Inhibitory interneurons are highly diverse, although the functional significance of their diversity is not yet well understood. This presents a barrier to understanding neural computation at the local circuit level. This review focuses on a recent study by Murayama et al. who used a novel in vivo technique in neocortex to demonstrate a specific sensory processing function of dendritic-targeting Martinotti interneurons. The function of Martinotti cells arises from their interaction with layer 5 pyramidal cell dendrites.
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