Science funding in low- and middle-income countries: the example of vaccine research

There has been a recent increase in funding sources and overall commitment to tackle global health issues and reduce morbidity and mortality. The Wellcome Trust, the UK's largest charity, has a long track record of funding research in global health and has developed a new research strategy to tackle these issues. Here, we describe the Wellcome Trust's approach to funding researchers in low- and middle-income countries with a focus on how our funding portfolio supports vaccine delivery and development, with specific reference to mucosal immunity.