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A mild, efficient method for the oxidation of alpha-diazo-beta-hydroxyesters to alpha-diazo-beta-ketoesters
Puhui Li1, Max M Majireck, Ilia Korboukh
1Department of Chemistry, The Pennsylvania State University, University Park, Pennsylania 16802 USA.
Abstract:
A wide variety of alpha-diazo-beta-ketoesters can be prepared in good overall yields via a two-step sequence involving addition of ethyl lithiodiazoacetate to aliphatic, aromatic and conjugated aldehydes followed by mild oxidation with the Dess-Martin periodinane.
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