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Wound healing effects of arnebia densiflora root extracts on rat palatal mucosa
H Huseyin Kosger1, Mustafa Ozturk, Atalay Sokmen
1Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cumhuriyet University, Sivas, Turkey.
Objectives:
The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa.
Methods:
A 10-mm full-thickness mucosal wounds were created on midline of rats' palate by using scalpel. In the experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically.
Results:
It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups.
Conclusions:
This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing.
