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Updated: Jun 23, 2026

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
Published on: April 12, 2019
Two base pair duplexes suffice to build a novel material
Martin Meng1, Carolin Ahlborn, Matthias Bauer
1Institut für Organische Chemie and Center for functional Nanostructures, Universität Karlsruhe (TH), 76131 Karlsruhe, Germany.
Abstract:
Tetrahedral DNA hybrids with tetrakis(p-hydroxyphenyl)methane cores hybridize in a sequence-specific fashion at much higher temperatures than isolated linear duplexes. Dinucleotide DNA arms suffice to induce the formation of a solid at room temperature; this demonstrates the strength of multivalent binding. The graphic shows a view of a modeled assembly.
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