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Glucose-6-phosphate dehydrogenase deficiency in a rural Saudi population
T H Saleem1, B S Mendis, S O Osanyintuyi
1Department of Biochemistry, Faculty of Medicine, Assuit University, Egypt.
The Journal of Tropical Medicine and Hygiene
|October 1, 1991
Insights
Glucose-6-phosphate dehydrogenase (G6PD) deficiency was studied in Saudi blood donors. The Al-Kharj region showed a low prevalence of 1.91%, one of the lowest in Saudi Arabia.
Area of Science:
- Medical Genetics
- Hematology
Background:
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited condition affecting red blood cells.
- Prevalence varies significantly across different populations and geographic regions.
Purpose of the Study:
- To determine the prevalence of G6PD deficiency among Saudi male blood donors in the Al-Kharj area.
- To compare findings with existing data on G6PD deficiency in Saudi Arabia.
Main Methods:
- Blood samples were collected from 3291 Saudi male blood donors.
- Glucose-6-phosphate dehydrogenase (G6PD) levels were analyzed.
Main Results:
- The prevalence of G6PD deficiency in the Al-Kharj population was found to be 1.91%.
- This prevalence is notably low compared to other reported rates in Saudi Arabia.
Conclusions:
- The Al-Kharj area exhibits a low prevalence of G6PD deficiency.
- Further research may be needed to understand the genetic and environmental factors influencing this low prevalence.
Abstract:
3291 Saudi male blood donors from a non-malarial area of Saudi Arabia were investigated for their glucose-6-phosphate dehydrogenase levels. The prevalence of glucose-6-phosphate dehydrogenase deficiency in the Al-Kharj area was 1.91% which is one of the lowest recorded in Saudi Arabia.