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Related Experiment Videos

How accurate is second trimester fetal dating?

F P Hadlock1, R B Harrist, J Martinez-Poyer

  • 1Department of Radiology, Baylor College of Medicine, Houston, Texas 77030.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|October 1, 1991
PubMed
Summary
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The Hadlock fetal dating models accurately estimate fetal age in the second trimester. Using multiple parameters significantly improves accuracy compared to single measurements for reliable pregnancy dating.

Area of Science:

  • Obstetrics and Gynecology
  • Prenatal Diagnosis
  • Fetal Medicine

Background:

  • Accurate fetal dating is crucial for optimal pregnancy management and clinical decision-making.
  • Existing fetal age estimation methods require validation across diverse populations and gestational windows.

Purpose of the Study:

  • To retrospectively evaluate the accuracy of Hadlock fetal dating models (single and multiple parameters).
  • To assess model performance specifically in chromosomally normal singleton fetuses during the second trimester of pregnancy (14-21 weeks).

Main Methods:

  • Retrospective analysis of 1770 chromosomally normal singleton fetuses.
  • Application of Hadlock models utilizing fetal head and femur measurements.
  • Comparison of single-parameter versus multiple-parameter model accuracy.

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Main Results:

  • Individual Hadlock models (head/femur) achieved a 95% confidence interval of +/- 1 week.
  • Multiple-parameter Hadlock models demonstrated statistically significant improvements in predicting fetal age.
  • Reduced both random and maximum observed errors in age prediction with multi-parameter models.

Conclusions:

  • Hadlock models are highly accurate for fetal age estimation in the second trimester.
  • Multi-parameter models offer superior predictive accuracy over single-parameter models.
  • These validated models support reliable dating between 14 and 42 weeks gestation.