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How accurate is second trimester fetal dating?

F P Hadlock1, R B Harrist, J Martinez-Poyer

  • 1Department of Radiology, Baylor College of Medicine, Houston, Texas 77030.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|October 1, 1991
PubMed
Summary

The Hadlock fetal dating models accurately estimate fetal age in the second trimester. Using multiple parameters significantly improves accuracy compared to single measurements for reliable pregnancy dating.

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Area of Science:

  • Obstetrics and Gynecology
  • Prenatal Diagnosis
  • Fetal Medicine

Background:

  • Accurate fetal dating is crucial for optimal pregnancy management and clinical decision-making.
  • Existing fetal age estimation methods require validation across diverse populations and gestational windows.

Purpose of the Study:

  • To retrospectively evaluate the accuracy of Hadlock fetal dating models (single and multiple parameters).
  • To assess model performance specifically in chromosomally normal singleton fetuses during the second trimester of pregnancy (14-21 weeks).

Main Methods:

  • Retrospective analysis of 1770 chromosomally normal singleton fetuses.
  • Application of Hadlock models utilizing fetal head and femur measurements.
  • Comparison of single-parameter versus multiple-parameter model accuracy.

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Main Results:

  • Individual Hadlock models (head/femur) achieved a 95% confidence interval of +/- 1 week.
  • Multiple-parameter Hadlock models demonstrated statistically significant improvements in predicting fetal age.
  • Reduced both random and maximum observed errors in age prediction with multi-parameter models.

Conclusions:

  • Hadlock models are highly accurate for fetal age estimation in the second trimester.
  • Multi-parameter models offer superior predictive accuracy over single-parameter models.
  • These validated models support reliable dating between 14 and 42 weeks gestation.