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Updated: Jun 23, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
Comparison of the in vitro activity of terbinafine and lanoconazole against dermatophytes
M A Ghannoum1, A Welshenbaugh, Y Imamura
1Center for Medical Mycology, University Hospital of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA. mahmoud.ghannoum@case.edu
Abstract:
The objective of this study was to compare the antifungal activity of terbinafine (TERB) with that of lanoconazole (LAN). Test isolates, which were clinical isolates of Japanese origin, included 10 strains each of Trichophyton rubrum, T. mentagrophytes and Epidermophyton floccosum. The minimum inhibitory concentration (MIC) of TERB and LAN against each dermatophyte isolate was determined according to the Clinical and Laboratory Standards Institute microbroth methodology, M38-A2. Minimum fungicidal concentrations were determined by subculturing the contents of each visibly clear well from the MIC assay for colony count. All LAN MICs were
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