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Cryptococcal disease presenting as necrotizing cellulitis in transplant recipients
S Baer1, J W Baddley, J W Gnann
1Augusta VA Medical Center, Augusta, Georgia 30904, USA. sbaer@mcg.edu
Abstract:
Disseminated cryptococcosis uncommonly presents with skin lesions in immunocompromised hosts. Necrotizing fasciitis, necrotizing vasculitis, myositis, or necrotizing soft tissue infection are even more rare presentations. We report 3 cases of cryptococcal necrotizing soft tissue infection, 2 in renal transplant patients, and 1 in a heart transplant patient, and discuss similar cases from the literature. Cryptococcus neoformans should be considered in the differential diagnosis of cellulitis or necrotizing soft tissue infections in immunocompromised patients.
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