Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thermosensation01:43

Thermosensation

Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
Body Temperature01:25

Body Temperature

The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
Thermoregulation01:26

Thermoregulation

The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
Assessing Body Temperature - Axilla01:14

Assessing Body Temperature - Axilla

Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Accessory Structures of the Skin: Sweat Glands01:20

Accessory Structures of the Skin: Sweat Glands

Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Temperature Measurement Sites01:14

Temperature Measurement Sites

A thermometer measures body temperature. The common sites for measuring body temperature are the oral cavity, axillary region, temporal artery, and skin surface, such as the forehead, abdomen, and axilla. True core body temperature is assessed in the rectum, tympanic membrane, pulmonary artery, esophagus, and urinary bladder.
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic responses in the human methylome to exertional heat exhaustion, heat injury, and heat stroke.

Human genomics·2026
Same author

Heat preparation and nutrition strategies for a 100-mile ultramarathon in extreme heat: A questionnaire study at the Western States Endurance Run.

Journal of science and medicine in sport·2026
Same author

Exertional Heat Illness in Active Populations.

NEJM evidence·2026
Same author

Dry and humid heat acclimation induces similar adaptations and cross-acclimation benefits in trained male cyclists.

The Journal of physiology·2026
Same author

Tribute to a great and unique thermal physiologist - Leo Charles Senay.

Temperature (Austin, Tex.)·2026
Same author

Regional body composition and human core temperature responses to mild temperature water immersion in adults.

Physiological reports·2025

Related Experiment Video

Updated: Jun 23, 2026

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device

Published on: November 24, 2016

A simple and valid method to determine thermoregulatory sweating threshold and sensitivity.

Samuel N Cheuvront1, Shawn E Bearden, Robert W Kenefick

  • 1US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Kansas St., Natick, MA 01760-5007, USA. samuel.n.cheuvront@us.army.mil

Journal of Applied Physiology (Bethesda, Md. : 1985)
|May 9, 2009
PubMed
Summary

This study validates segmented linear regression (SReg) as a simple, standardized method for determining sweating threshold temperature and sweating sensitivity. SReg offers a reliable approach for thermoregulatory control research.

More Related Videos

Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

A Protocol of Manual Tests to Measure Sensation and Pain in Humans
07:28

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

Published on: December 19, 2016

Related Experiment Videos

Last Updated: Jun 23, 2026

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device

Published on: November 24, 2016

Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

A Protocol of Manual Tests to Measure Sensation and Pain in Humans
07:28

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

Published on: December 19, 2016

Area of Science:

  • Physiology
  • Thermoregulation
  • Biomedical Engineering

Background:

  • Thermoregulatory control is assessed via sweating threshold temperature and sensitivity.
  • Current analytical methods lack standardization and validation.
  • Varied approaches hinder consistent interpretation of thermoregulatory data.

Purpose of the Study:

  • To validate segmented linear regression (SReg) as a standardized method for determining sweating threshold temperature and sensitivity.
  • To compare SReg with existing empirical methods used by experienced raters.
  • To establish a reliable and simple analytical tool for thermoregulatory studies.

Main Methods:

  • Utilized archived data from local arm sweat rate (m(sw)) and esophageal temperature (T(es)) measurements.
  • Analyzed 16 experimental datasets using SReg and compared with seven experienced raters' empirical methods.
  • Employed a modified Bland-Altman approach to evaluate interrater and Rater-SReg differences within biologically relevant limits of magnitude (LOM).

Main Results:

  • Interrater differences were within LOM for 95% (threshold) and 73% (sensitivity) of observations.
  • Differences between mean rater results and SReg were within LOM for 90% (threshold) and 83% (sensitivity) of comparisons.
  • No statistically significant differences were found between rater and SReg outputs (P > 0.05).

Conclusions:

  • Segmented linear regression (SReg) is a simple and valid method for determining sweating threshold temperature and sensitivity.
  • SReg provides a standardized approach, enhancing consistency in thermoregulatory research.
  • This validated method improves the reliability of analyzing sweating responses in physiological studies.