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Updated: Jun 23, 2026

Comparison of Two Representative Methods for Differentiation of Human Induced Pluripotent Stem Cells into Mesenchymal Stromal Cells
Published on: October 20, 2023
Mesenchymal stem cells in the induction of transplantation tolerance
Amelia Bartholomew1, David Polchert, Erzsebet Szilagyi
1Department of Surgery, University of Illinois-Chicago, Chicago, IL 60612, USA. ambart@uic.edu
Abstract:
Mesenchymal stem cells directly suppress ongoing immune responses. Through production of toleragenic cytokines, inhibition of lymphocyte proliferation, delivery of reparative and protective signals after reperfusion injury, and facilitation of hematopoietic chimerism, these cells demonstrate a wide-ranging potential for the development of multifaceted toleragenic strategies after transplantation.
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