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Astemizole-induced cardiac conduction disturbances in a child
J R Tobin1, T P Doyle, A D Ackerman
1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205.
JAMA
|November 20, 1991
Abstract:
The newly available antihistamine astemizole (Hismanal) has been previously associated with hemodynamically significant cardiac tachydysrhythmias. We describe a 3-year-old girl who developed multiple different cardiac dysrhythmias after an astemizole overdose. No hemodynamic compromise occurred, and the electrocardiogram returned to normal without use of antiarrhythmic agents within 7 hours.