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[Sweet's syndrome with pregnancy].

C Inoue1, A Mochizuki, M Okuda

  • 1Department of Dermatology, Teikyo University School of Medicine.

Nihon Hifuka Gakkai Zasshi. the Japanese Journal of Dermatology
|August 1, 1991
PubMed
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This case study presents a pregnant woman diagnosed with Sweet's syndrome, a rare skin condition. Treatment with prednisolone was successful, with no relapse after delivery, highlighting effective management during pregnancy.

Area of Science:

  • Dermatology
  • Immunology

Background:

  • Sweet's syndrome is an acute febrile neutrophilic dermatosis.
  • It is often associated with underlying systemic conditions like collagen diseases or malignancies.
  • Pregnancy-associated Sweet's syndrome is rare, with few reported cases globally.

Observation:

  • A 31-year-old pregnant woman presented with characteristic skin eruptions on her wrist, face, and neck.
  • Clinical, histopathological, and laboratory findings confirmed the diagnosis of Sweet's syndrome.
  • Polymorphonuclear leukocyte (PMN) activity was found to be elevated in the patient compared to controls.

Findings:

  • Successful treatment of pregnancy-associated Sweet's syndrome was achieved using prednisolone.
  • The patient experienced no relapse of symptoms postpartum.

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  • This represents the first reported case of Sweet's syndrome associated with pregnancy in Japan.

    • Implications:

    • This case demonstrates the safety and efficacy of prednisolone for managing Sweet's syndrome during pregnancy.
    • It contributes to the limited literature on pregnancy-associated Sweet's syndrome, particularly from Japan.
    • Further research into the immunological aspects, such as PMN activity, may elucidate the pathogenesis of this condition in pregnant individuals.