Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of a pharmacist-led digital hypertension management program in a tertiary hospital in Singapore.

Digital health·2026
Same author

Impact of Type 2 Diabetes Mellitus and Chronic Kidney Disease on Bone Mineral Density in Elderly Patients With Fragility Hip Fracture: A Cross-Sectional Study.

Aging medicine (Milton (N.S.W))·2025
Same author

Predictive value of donor kidney quality assessment and risk quantification scores on 5-year outcomes of deceased donor kidney transplantation.

International urology and nephrology·2024
Same author

Diagnostic threshold and performance of anion gap in screening for high anion gap metabolic acidosis.

Singapore medical journal·2024
Same author

Evaluation of factors associated with bleeding following haemodialysis catheter-related procedures and the risk with anti-platelet agents.

The journal of vascular access·2023
Same author

25-OH vitamin D threshold for optimal bone mineral density in elderly patients with chronic kidney disease.

Frontiers in aging·2022
Same journal

Intracardiac Vascular Access for Hemodialysis Despite Associated Ascending Aortic Aneurysm.

Seminars in dialysis·2026
Same journal

Measures of Equivalent Hemodialysis Urea Clearance and Their Proposed Utility for Monitoring Adequacy.

Seminars in dialysis·2026
Same journal

Risk of Serious Adverse Events and Death With Low-Dose Methotrexate Versus Hydroxychloroquine in Adults Receiving Dialysis.

Seminars in dialysis·2026
Same journal

Severe Hematoma Following Initial Arteriovenous Fistula Puncture in a Hemodialysis Patient, Emphasizing Thoracic Outlet Syndrome: A Case Report.

Seminars in dialysis·2026
Same journal

Phosphate Kinetic Modeling in Patients Treated With Hemodialysis or Hemodiafiltration: A Prospective, Multicenter, Cross-Sectional Study.

Seminars in dialysis·2026
Same journal

Impact of Expanded Hemodialysis on Inflammation and Iron Metabolism in Chronic Hemodialysis Patients.

Seminars in dialysis·2026
See all related articles

Related Experiment Video

Updated: Jun 23, 2026

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
09:43

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

Published on: August 10, 2015

Machines for continuous renal replacement therapy.

Dinna Cruz1, Ilona Bobek, Paolo Lentini

  • 1Department of Nephrology, St. Bortolo Hospital, Vicenza, Italy.

Seminars in Dialysis
|May 12, 2009
PubMed
Summary
This summary is machine-generated.

Advancements in continuous renal replacement therapy (CRRT) include new machines and techniques like high-volume hemofiltration. These innovations aim to improve outcomes for critically ill patients with acute renal failure.

More Related Videos

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

Related Experiment Videos

Last Updated: Jun 23, 2026

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development
09:43

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

Published on: August 10, 2015

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

Area of Science:

  • Critical care nephrology
  • Renal replacement therapy technology

Background:

  • Continuous renal replacement therapy (CRRT) has seen significant technological evolution.
  • Understanding of acute renal failure pathophysiology has also advanced.

Purpose of the Study:

  • To review advancements in CRRT technology and their impact.
  • To highlight improvements in patient care and outcomes.

Main Methods:

  • Review of technological developments in CRRT machines and techniques.
  • Discussion of new biomaterials and devices.

Main Results:

  • Successful extensions of CRRT include high volume and high permeability hemofiltration.
  • New CRRT machines offer user-friendly interfaces, automated priming, and flexible fluid management (predilution/postdilution).
  • Sorbent technology has been successfully integrated.

Conclusions:

  • Technological progress in CRRT is substantial, with new devices and biomaterials emerging.
  • Further advancements are anticipated to improve morbidity and mortality in critically ill patients.
  • CRRT technology has significantly progressed, enhancing critical care nephrology.