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Updated: Jun 23, 2026

A Mouse Distraction Osteogenesis Model
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A Mouse Distraction Osteogenesis Model

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Vertical distraction osteogenesis using a titanium nitride-coated distractor.

Kye-Joon Yi1, Su-Gwan Kim, Seong-Yong Moon

  • 1Department of Oral and Maxillofacial Surgery, College of Dentistry, Chosun University, GwangJu City, South Korea.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
|May 12, 2009
PubMed
Summary

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Titanium nitride (TiN)-coated distractors show promising results for vertical distraction osteogenesis. These coated devices do not negatively impact osseointegration, suggesting they can effectively replace conventional distractors.

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Orthodontics

Background:

  • Vertical distraction osteogenesis is crucial for bone augmentation.
  • Titanium nitride (TiN) coatings offer potential benefits for medical implants.
  • Assessing the biocompatibility and osseointegration of novel coated devices is essential.

Purpose of the Study:

  • To evaluate the effect of TiN-coated vertical distractors on osseointegration.
  • To compare TiN-coated distractors with conventional titanium distractors in a canine model.

Main Methods:

  • Vertical distraction was performed on the lower premolars of four mongrel dogs.
  • Distraction devices, either titanium or TiN-coated, were used.
  • Histological examination assessed osseointegration after implant placement and healing periods.

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Last Updated: Jun 23, 2026

A Mouse Distraction Osteogenesis Model
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An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
09:26

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Published on: October 23, 2017

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Main Results:

  • All implants achieved a 100% success rate.
  • Direct bone-to-implant contact was observed in all groups.
  • No significant differences in osseointegration were found between TiN-coated and conventional titanium distractors.

Conclusions:

  • TiN-coated distraction devices do not adversely affect osseointegration.
  • These coated devices hold potential as effective substitutes for conventional distractors in vertical distraction osteogenesis.
  • Further research may explore long-term outcomes and clinical applications.