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Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Improving Translational Accuracy02:07

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Cell Diversity01:13

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The concept of a cell started with microscopic observations of dead cork tissue by Robert Hooke in 1665. Hooke coined the term "cell" based on the resemblance of the small subdivisions in the cork to the rooms that monks inhabited, called cells. About ten years later, Antonie van Leeuwenhoek became the first person to observe the living and moving cells under a microscope. In the century that followed, the theory that cells represented the basic unit of life developed.
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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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Intercell - accelerating innovation.

Marc Brehme1

  • 1CeMM - Research Center for Molecular Medicine, Austrian Academy of Sciences, c/o Vienna Competence Center, Lazarettgasse 19, 3, 1090 Vienna, Austria. mbrehme@cemm.oeaw.ac.at

New Biotechnology
|May 12, 2009
PubMed
Summary
This summary is machine-generated.

This interview features Alexander von Gabain, CSO of Intercell, a leader in innovative vaccine development. Learn about the company's advancements in creating next-generation vaccines.

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Area of Science:

  • Biotechnology
  • Vaccinology
  • Infectious Disease Research

Background:

  • Intercell is a prominent company specializing in vaccine development.
  • Alexander von Gabain, Chief Scientific Officer, shares insights into the company's work.

Discussion:

  • The interview likely covers Intercell's strategies and technological approaches in vaccine creation.
  • Key challenges and breakthroughs in the field of vaccine development may be discussed.

Key Insights:

  • Intercell is positioned at the forefront of vaccine innovation.
  • The discussion offers a glimpse into the operational and scientific aspects of a leading vaccine company.

Outlook:

  • Future directions in vaccine research and development at Intercell.
  • Potential impact of Intercell's work on public health and disease prevention.