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Orthostatic hypertension: a measure of blood pressure variation for predicting cardiovascular risk

Kazuomi Kario1

  • 1Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke 329-0498, Japan. kkario@jichi.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society
|May 12, 2009
PubMed

Insights

Orthostatic hypertension, a blood pressure variability measure, signals cardiovascular risk and precedes hypertension. Home blood pressure monitoring can detect this condition, aiding early intervention.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Measurement

Background:

  • Orthostatic hypertension is a significant indicator of blood pressure variability.
  • It is linked to target organ damage and increased cardiovascular risk.
  • This condition can precede the development of established hypertension.

Purpose of the Study:

  • To highlight the clinical significance of orthostatic hypertension.
  • To emphasize its role as a potential precursor to hypertension.
  • To discuss the utility of home blood pressure monitoring in its detection.

Main Methods:

  • Utilizing self-measured home blood pressure monitoring.
  • Analyzing orthostatic blood pressure changes.
  • Assessing reproducibility and the absence of the white-coat effect.

Main Results:

  • Orthostatic hypertension is associated with morning hypertension.
  • Increased neurohumoral activation is observed in patients with orthostatic hypertension.
  • Home monitoring offers reproducible detection of abnormal orthostatic BP changes.

Conclusions:

  • Orthostatic hypertension is a clinically relevant condition preceding hypertension.
  • Home blood pressure monitoring is a viable method for detecting orthostatic hypertension.
  • Further research is needed to elucidate the precise mechanisms underlying orthostatic hypertension.

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